Many of the most severe side effects associated with the use of  SSRI Antidepressants such as Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Lexapro (escitalopram) and Celexa (citalopram) are congenital birth defects,  including: Congenital Heart Defects, Congenital Lung Defects, Congenital Abdominal Wall Defects, Congenital Cranio-facial Defects,and other birth defects and malformations affecting various other areas of the child’s anatomy.

SSRI Antidepressant Heart Birth Defects

According to scientific studies, women who take SSRI Antidepressants such as Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Lexapro (escitalopram) and Celexa (citalopram) are at least twice as likely to give birth to children with serious congenital heart defects.  A congenital heart defect is a problem with the structure of the heart present at birth. Congenital heart defects are the most common type of major birth defect.  A baby’s heart begins to develop shortly after conception and during the first tri-mester. During development, structural defects can occur. These defects can involve the walls of the heart, the valves of the heart and the arteries and veins to and from the heart. Congenital heart defects can disrupt the normal flow of blood through the heart, lungs and body.

What is Tricuspic Atresia?

Tricuspid atresia is a type of congenital heart disease in which the tricuspid heart valve is missing or abnormally developed. The defect blocks blood flow from the right atrium to the right ventricle.

Causes

Tricuspid atresia is an uncommon form of congenital heart disease that affects about 5 in every 100,000 live births. Twenty percent of patients with this condition will also have have other heart problems.

Normally, blood flows from the body into the right atrium, then through the tricuspid valve to the right ventricle and on to the lungs. If the tricuspid valve does not open, the blood cannot flow from the right atrium to the right ventricle. Blood ultimately cannot enter the lungs, where it must go to pick up oxygen (become oxygenated).

Infants with tricuspid atresia generally are cyanotic (bluish discoloration of skin) and easily become short of breath.

Symptoms

•Cyanosis (bluish discoloration of the skin)
•Easily fatigued
•Shortness of breath (dyspnea)
•Fast breathing
•Poor growth

Exams and Tests

This condition may be discovered during routine prenatal ultrasoundprenatal ultrasound imaging or when the baby is examined shortly after birth. Cyanosis is present from birth. A heart murmur is often present at birth and may increase in loudness over several months.

Tests may include the following:

•ECGECG
•Echocardiogram
•Chest x-rayChest x-ray
•Cardiac catheterization
•MRI of the heartMRI of the heart

Treatment

Once the diagnosis is made, the baby will be admitted to the neonatal intensive care unit (NICU). A breathing machine (ventilator) may be needed to help the baby breathe. A medicine called prostaglandin E1 is used to maintain circulation of blood to the lungs.

The condition always requires surgery. If the heart is unable to pump enough blood out to the lungs and rest of the body, the first surgery usually occurs within the first few days of life. In this procedure, an artificial shunt is inserted to maintain blood flow to the lungs. In some cases, this first surgery is not necessary.

Afterwards, the baby usually goes home. The child will need to take one or more daily medicines and be closely followed by a pediatric cardiologist, who will determine when the second stage of surgery should be done.

Stage II of the operation is called the Glenn shunt or Hemifontan procedure. This procedure connects half of the veins carrying blue blood from the upper half of the body directly to the pulmonary artery. The surgery is usually done when the child is between 4 – 6 months of age.

During stage I and II, the child may still appear somewhat blue (cyanotic).

Stage III, the final step, is called the Fontan procedure. The remainder of the veins carrying blue blood from the body is connected directly to the pulmonary artery leading to the lungs, and the left ventricle now only has to pump to the body and no longer the lungs. This surgery is usually performed between the ages of 18 months and 3 years of age. After this final step, the baby is no longer blue (cyanotic).

Some patients may need more surgeries in their 20s or 30s if they develop hard to control arrhythmias or other complications of the Fontan procedure.

In a few hospitals, heart transplantation is considered to be a better alternative to the 3-step surgery process, but there are few donated hearts available for small infants.

Outlook (Prognosis)

Improvement can be expected with most surgical procedures. Unexpected death may occur with heart arrhythmias.

Possible Complications
•Irregular, fast heart rhythms (arrhythmias)
•Chronic diarrhea (from a disease called protein loosing enteropathy)
•Heart failure
•Fluid in the abdomen (ascites) and in the lungs (pleural effusion)
•Blockage of the artificial shunt
•Strokes and other neurological complications
•Sudden death

When to Contact a Medical Professional

If your infant has new changes in breathing patterns, eats less (decreased feeing), or has skin or mucous membranes that are turning blue (cyanotic), contact your health care provider immediately.

Prevention

There is no known way to prevent tricuspid atresia.

Alternative Names

Tri atresia

SSRI Class Action Lawsuit vs. Individual SSRI Lawsuit

There are distinct differences between an SSRI Antidepressant (Zoloft – sertraline, Paxil – paroxetine, Prozac – fluoxetine, Lexapro – escitalopram and Celexa – citalopram) class action lawsuit and a more typical individual SSRI lawsuit. A SSRI class action lawsuit would be a form of SSRI lawsuit in which a large group of people (plaintiffs) collectively bring a lawsuit to court in the form of a “class action” against the manufacturers of the SSRI antidepressant (defendant). In a class action lawsuit involving personal injury, resulting from defective products such as antidepressant SSRI drugs like Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Lexapro (escitalopram) and Celexa (citalopram), all SSRI lawsuit plaintiffs would typically be grouped together into a single SSRI class action lawsuit, regardless of the degree or severity of their birth defect injuries. In this type of SSRI class action lawsuit, plaintiffs with injuries ranging from minor heart murmurs not requiring surgery, all the way to the most severe congenital heart defects, requiring multiple surgeries or a complete heart transplant, would be grouped into one single SSRI class action lawsuit. All plaintiffs in the class would equally share any award or settlement resulting from the SSRI class action lawsuit.

In SSRI antidepressant lawsuits involving catastrophic injury or death, an individual lawsuit, in most cases, is more appropriate and in the plaintiff’s best interest. SSRI antidepressants like Zoloft, Prozac, Celexa, Lexapro and Paxil, have been linked to some of the severe congenital heart defects listed above, including: atrial septal defects (ASD – hole in the heart), ventricular septal defects (VSD – hole in the heart), tetrology of fallot (ToF), hypoplastic left heart syndrome (HLHS), transposition of the great arteries (TGA or TOGA), patent ductus arteriosus (PDA), total anomalous pulmonary venous return (TAPVR), double outlet right ventricle (DORV), and coarctation of the aorta (CoA). SSRI antidepressant cases such as these are better suited to an individual SSRI antidepressant lawsuit because of the severity and degree of injury to the plaintiff. In an individual SSRI lawsuit, each plaintiff’s case is filed, presented and considered individually, based on its own strength and degree of injury.

In many cases involving SSRI antidepressants like Zoloft, Prozac, Celexa, Lexapro, Paxil and the serious congenital heart defects related to these SSRI antidepressants, surgery is required. Heart surgery will typically be required when a child is an infant or toddler and then again, potentially multiple times, as the child grows to maturity. In many cases, with surgery and medical care, children may be able to lead mostly normal and productive lives. An individual SSRI lawsuit allows each SSRI victim, their injuries and their future needs to be considered on an individual basis when determining damages, awards and settlement amounts, and not as part of a class action lawsuit.

Speak to an SSRI Lawyer about an SSRI Birth Defect Lawsuit

If you took Prozac (fluoxetine), Paxil (paroxetine), Zoloft (sertraline), Celexa (citalopram), Lexapro (escitalopram) or any another SSRI antidepressant drug during pregnancy and your child was born with a congenital heart, lung or other birth defect, we encourage you to contact an SSRI Antidepressant Lawsuit Attorney at our law firm immediately. It may be too late to recover from the devastating effects of Prozac, Paxil, Zoloft, Lexapro and Celexa but an experienced pharmaceutical products liability lawyer at the Willis Law Firm can assist you in legal action against the makers of these dangerous antidepressant drugs. You are not alone. Join other birth defect victims and their families in speaking up and fighting for your legal rights.

Please fill out our free online legal evaluation form and we will contact you within 24 hours, or call our offices at 1-800-883-9858 for immediate help. Please keep in mind that certain states have statutes of limitation that limit the amount of time you have to file a lawsuit or seek legal action. Contact our law firm immediately so that we may explain the rights and options available to you and your family.